granular cell tumor on perianal region: a case report.

Authors

kesici ugur department of general surgery, ministry of health, akcaabat hackali baba state hospital, trabzon, turkey.

mataraci emine department of pathology, ministry of health, akcaabat hackali baba state hospital, trabzon, turkey.

kesici sevgi department of anaesthesiology and reanimation, ministry of health, kanuni training and research hospital, trabzon, turkey.

zeren sezgin department of general surgery,ministry of health, numune hospital, sivas, turkey.

abstract

granular cell tumor (gct) was first described by abrikossoff in 1926. gct is a rarely seen soft tissue tumor and is generally benign. while the tumor can be seen in all parts of the body it is generally located on the head and neck region, and especially on the tongue. gct is rarely seen in the anal-perianal region. in accordance with literature this case was reported because it was thought to be the 27th anal-perianal located gct case. in this case report, approximately 0,5-1 cm pedunculated polypoid lesion was determined in the perianal region during the physical examination of a 23 year old female patient who applied with palpable mass complaint in the perianal region. lesion in the patient was totally excited with healthy skin-subcutaneous tissue under local anesthesia. a benign granular cell tumor was detected in the histopathological examination. positive staining was monitored immunohistochemically with s-100 and neuron specific enolase (nse). gct is a rarely seen tumor in the anal-perianal region and its malign transformation rate is very low. even lesions seen in the perianal region have clinically a benign appearance, a histopathological examination should be conducted and also gct should be kept in mind during diagnosis. malign-benign separation of these lesions is difficult so histopathological examination should be conducted with great care. large local excision in the treatment provides curative treatment. but for those presenting malign transformation further examination must be performed for metastasis. after the treatment local recurrence and metastasis should be considered carefully. prognosis of metastatic disease is very bad.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Cutaneous granular cell tumor: case report

Background: Granular cell tumor (Abrikossoff’s tumor) is a rare and slow-growing tumor of the soft tissue. Originated from the Schwann cells, it is often a benign tumor, but it can be malignant in 1-3% of the cases. Malignant cases can cause significant morbidity and mortality. It may develop in many anatomic locations, especially in the head and neck region, and also in skin and subcutaneous t...

full text

Coexistence of Granular Cell Tumor with Squamous Cell Carcinoma on the Tongue: A Case Report

Introduction: Granular cell tumors (GCTs) are rare and mostly benign soft tissue tumors. Though they have been reported in all parts of body, they are generally located in the head and neck region, especially on the tongue. Some malign forms exist, but these have been rarely reported. Granular cell tumors have a neural origin and, in immunohistochemical evaluations, they express S-100 and neuro...

full text

A rare case of perianal granular cell tumor: case report and literature review

Granular cell tumor (GCT) is a rare submucosal neoplasm most commonly localized in the oral mucosa; with one-third of all cases found in the tongue, with less than 30 cases of perianal GCT reported in the literature, making it a rare anal neoplasm. Wide local excision is the gold standard of treatment and follow-up includes annual colonoscopy due to the high incidence of reoccurrence. Here we d...

full text

Perianal granular cell tumor: report of a case and review of the literature.

INTRODUCTION Granular cell tumor was first described by Abrikossoff in 1926. Over the years several cases of this neoplasm have been reported, with a variety of localizations. We here report a case of perianal granular cell tumor and discuss its histogenesis and its relevance to clinical practice. METHODS The clinical course and histopathology of the case are reviewed, and a literature search...

full text

Neural granular cell tumor. A case report.

It is presented the case of an old female with a solitary tumor at the level of the thorax. The specimen was processed using the routine histological technique and slides were stained with conventional morphologic, histochemical and immunohistochemical methods. On Hematoxylin-Eosin stained slides were noticed large cells with acidophilic cytoplasm, with granular pattern. S100 protein was intens...

full text

Endobronchial granular cell tumor: a case report.

Granular cell tumors (GCTs) are benign neoplasms that are most commonly found in the head and neck region. We present a case of endobronchial granular cell tumor presenting as hemoptysis in a 22-year-old African American female. Patient subsequently underwent a right upper and middle lobectomy, and upon histologic analysis was found to have GCT with borders impinging upon cartilage and adjacent...

full text

My Resources

Save resource for easier access later


Journal title:
acta medica iranica

جلد ۵۱، شماره ۷، صفحات ۵۰۹-۵۱۱

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023